The Effect Of Domperidone Toward Breast Milk Production On Sectio Caesarea Mother

Sri Dinengsih, Sri Dinengsih and Cholisah Suralaga, Cholisah Suralaga (2020) The Effect Of Domperidone Toward Breast Milk Production On Sectio Caesarea Mother. Jurnal Ners & Kebidanan Indonesia (Indonesian Journal of Nursing & Midwifery, 8 (4). pp. 286-291. ISSN 2503-1856

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Abstract

Mothers that give birth with section caesaria (SC) often experience difficulty to get a
adequate breast milk production. Various kinds of effort have been conducted to overcome
this problem, including pharmacological intervention. One of the medicines that could be
possibly used is domperidon. Domperidon is an antagonist receptor of peripheral dopamine
that works by choking inhibition effect of prolactin secretion facilitated by dopamine to
improve breast milk production.The research aimed to unveil the effect of domperidon
toward breast milk production on mother that give birth with SC in Indonesia. This is a
quasi-experiment research with two groups post-test only design. The sample of this
research 30 were post sectio caesarea patients consisting of 15 patients in intervention
group and 15 patients in control group. Purposive sampling was used in the research
to get the samples. The instrument used was observation sheets. Result analysis was
conducted by calculating the frequency distribution and bivariate analysis with Mann
Whitney test. The average score of breast milk production among post-SC mother in the
intervention group was 22,60, while the average score of breast milk production among
post-SC mother in control group was 15,47, Asymp. value Sig (2 tailed) 0,020 (0,020 <
0,05). Domperidone has been approved to have a significant effect to improve breast milk
ISSN 2354-7642 (Print), ISSN 2503-1856 (Online)
Jurnal Ners dan Kebidanan Indonesia
Tersedia online pada:
http://ejournal.almaata.ac.id/index.php/JNKI
INDONESIAN JOURNAL OF NURSING
AND MIDWIFERY
The Effect Of Domperidone Toward Breast Milk Production On Sectio Caesarea Mother 287
INTRODUCTION
Breast milk production is a process of
releasing oxytocin hormone to floe breast milk
produced within breast. The problem of early
releasing breast milk could happen to mothers
who experience sectio caesaria; it could result in
bad impact toward the infant because new born
baby needs colostrum. Post-SC mothers will face
difficulty in early breastfeeding initiation because
of rooming-in factor, SC wound, and weakness
because of anesthesia, therefore post-SC patient
could do breastfeeding her infant several hours
after labor (1).
WHO recommends that newborns should
receive exclusive breastfeeding for six months
because breast milk is the best natural nutrition
for babies with the most suitable nutritional
content for optimal growth (2). UNICEF confirms
that formula-fed babies have a 25 times higher
chance of dying in the first month of birth and
formula-fed babies are 25 times higher than
babies who are exclusively breastfed (3).
The coverage of exclusive breastfeeding
in Indonesia is still low, namely 37.3% of babies
in Indonesia who are exclusively breastfed. It
means that there are 2/3 of babies in Indonesia
who are not breastfed exclusively. In Indonesia,
the number of SC births is high. According to
national survey data 2018 there were around
28.9% of all deliveries (4).
Mothers with SC will experience anesthesia
and postoperative pain so they are not free to
breastfeed their babies intensely. Besides, after
surgery mother must be moved to the Recovery
Room. Although, currently, implementing early
breastfeeding initiation (IMD) can also be done
in the operating room, not all hospitals have the
same policy. In addition, the feeling of the mother
who is not sure that she can give breast milk to
her baby because of the condition will cause a
decrease in oxytocin so the milk cannot come
out immediately after giving birth and finally the
mother decides to give formula milk(5).
Domperidone is known to be used as a
breast milk booster among nursing mothers. IDAI
stated that domperidone used as a lactogogue
(a substance that can be trusted to increase
milk production) was first reported in 1983. This
substance increases prolactin serum in lactating
women. Side effects of domperidone are very
rare, including dry mouth, headache (relieves
with reduced dose) and stomach cramps. Longterm high-dose domperidone treatment in mice
was associated with an increase in the number
of breast tumors. This has never been reported
in humans (6).
In Asia and Europe, domperidone has long
been used as a prokinetics and antiemetic. The
clinical use of domperidone is in the treatment
of gastroesophageal reflux disease, diabetic
gastroparesys, chronic dyspepsia, and is
sometimes recommended to stimulate postpartum lactation. Domperidone is the most
recommended medicine because it has been
production on post-SC mothers. Improving breast milk production could be conducted
non-pharmacologically, but pharmacological therapy could also be considered if the nonpharmacological therapy doesn’t work well in improving breast milk production.
Keywords: domperidone; production breast milk; sectio caesar

Item Type:	Article
Uncontrolled Keywords:	domperidone; production breast milk; sectio caesar
Subjects:	R Medicine > R Medicine (General) R Medicine > RT Nursing
Divisions:	Faculty of Medicine, Health and Life Sciences > School of Medicine
Depositing User:	Mrs Ni Made Yunia Dwi Savitri
Date Deposited:	02 Jun 2022 01:37
Last Modified:	02 Jun 2022 01:37
URI:	http://eprints.triatmamulya.ac.id/id/eprint/1076

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